Inhibitory effects of guarana seed extract on passive cutaneous anaphylaxis and mast cell degranulation.
نویسندگان
چکیده
This study investigated the effects of guarana seed extract (GSE) on an anti-allergic mechanism. GSE orally administered inhibited the anti-dinitrophenol IgE-induced passive cutaneous anaphylaxis reaction in mice. Furthermore, it inhibited the degranulation of rat basophilic leukemia RBL-2H3 cells. It had no cytotoxicity on RBL-2H3 cells. These results show that GSE is a candidate for effective therapeutic material for allergic diseases.
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ورودعنوان ژورنال:
- Bioscience, biotechnology, and biochemistry
دوره 73 9 شماره
صفحات -
تاریخ انتشار 2009